Title of article :
Synthesis of the C1-C5 and C6-C24 Fragments of the RNA Polymerase Inhibitors Ripostatin A and B
Author/Authors :
Kujat، Christof نويسنده , , Bock، Martin نويسنده , , Kirschning، Andreas نويسنده ,
Abstract :
The enantioselective synthesis of the C1-C5 and C6-C24 fragments of the ripostatins utilize a Negishi coupling, two Nagao acetate aldol reactions followed by a Denmark vinylogous aldol reaction and Stille couplings as key C-C bond forming steps.
Keywords :
RNA polymerase inhibitors , vinylogous aldol reaction , antibiotics , Nagao aldol reaction , natural product synthesis
Journal title :
Astroparticle Physics
