Palladium-Catalyzed Negishi Cross-Coupling of Arylzinc Reagents with Functionalized Vinylic Tellurides

The Negishi cross-coupling reaction of arylzinc chlorides and bromides with functionalized vinylic tellurides in the ­presence of a catalytic amount of PdCl2 in THF at room temperature is described. This cross-coupling reaction is general and permits the synthesis of functionalized substituted alkenes in good yields and high stereoselectivity.