Title of article :
Synthesis of Novel Bicyclic Ketals of Galacturonic Acid as Potential Glycosidase Inhibitors
Author/Authors :
Harms، Klaus نويسنده , , Koert، Ulrich نويسنده , , Rommel، Michael نويسنده , , Ernst، Alexander نويسنده ,
Abstract :
A synthesis of novel bicyclic ketals of galacturonic acid is described. The key cyclisation step was realised under acidic anhydrous conditions in very good yield. X-ray crystal structure analysis determined the correct regio- and stereochemistry.
Keywords :
galactose , lactol Wittig reaction , (delta)-amino acids , glycosidase inhibitors , bicyclic acetal/ketal
Journal title :
Astroparticle Physics
