Title of article :
Two Protocols for the Conversion of Biphenol to Binaphthol: Synthesis of Diospyrol
Author/Authors :
Thasana، Nopporn نويسنده , , Pisutjaroenpong، Somchai نويسنده , , Ruchirawat، Somsak نويسنده ,
Abstract :
The application of directed orthometallation (DoM), Fries rearrangement and transmetallation followed by allylation and cyclization is reported for the conversion of biphenol to binaphthol as a means for the synthesis of diospyrol. Furthermore, the same transformation can be accomplished by the reaction of the dienolate anion of an (alpha),(beta)-unsaturated amide with an aryne intermediate.
Keywords :
Biaryls , arynes , ring closure , directed orthometallation , Fries rearrangement
Journal title :
Astroparticle Physics
