Title of article :
Studies on the Base-Catalysed Addition of Amines to Alkynes and Allenes: A Novel Cascade Sequence for the Construction of Spirocyclic Aminals
Author/Authors :
Hitchcock، Peter B. نويسنده , , Parsons، Philip J. نويسنده , , Hoenke، Nicole نويسنده , , Payne، Lloyd J. نويسنده ,
Abstract :
Indoles can be prepared by the intramolecular addition of resin bound amides to allenyl sulfoxides. Amino alkynols have been converted into spirocyclic aminals in one synthetic operation representing an enormous increase in molecular complexity.
Keywords :
Amine , Cascade , Alkyne , allene sulfoxide , combinatorial chemistry , spirocyclic
Journal title :
Astroparticle Physics
