Title of article :
Enantioselective Synthesis of (beta)-Lactams Using a Chiral Auxiliary
Author/Authors :
Jian، Shan-Zhong نويسنده , , Wang، Yan-Guang نويسنده , , Yuan، Qing نويسنده ,
Abstract :
An efficient and enantioselective synthesis of trans-(beta)-lactams from carboximide 1 and imines 2 using a chiral auxiliary under the classical Reformatsky reaction conditions is described. An enolate-imine mechanism has been proposed for this reaction.
Keywords :
Imines , enantioselectivity , Reformatsky reaction , (beta)-lactams
Journal title :
Astroparticle Physics