Title of article :
Addition of Lithiated Tertiary Aromatic Amides to Epoxides and Aziridines: Asymmetric Synthesis of (S)-(+)-Mellein
Author/Authors :
Helliwell، Madeleine نويسنده , , Clayden، Jonathan نويسنده , , Stimson، Christopher C. نويسنده , , Keenan، Martine نويسنده ,
Abstract :
Addition of ortholithiated or laterally lithiated amides to epoxides or aziridines provides, in some cases stereoselectively, products which may cyclise to yield benzopyranones in good enantiomeric excess.
Keywords :
directed metallation , synthesis , isochromanone , epoxide , lithiation , benzopyranone
Journal title :
Astroparticle Physics
