Author/Authors :
Inoue، Seiichi نويسنده , , Hoshino، Yujiro نويسنده , , Honda، Kiyoshi نويسنده , , Nakagawa، Chihiro نويسنده , , Hayakawa، Hidetaka نويسنده , , Iwasaki، Fumiyoshi نويسنده ,
Abstract :
Regioselective synthesis of the model compound of NG-121 was achieved. The key steps are ortho-alkylation of the phenol via [2,3]sigmatropic rearrangement of a sulfur ylide and the regioselective construction of the attached lactone ring.
Keywords :
Ylides , sigmatropic rearrangement , regioselective formylation , lactones , Phenols
