• Title of article

    Efficient Microwave-Assisted Synthesis of Tetrahydroindazoles and their Oxidation to Indazoles

  • Author/Authors

    Cavaleiro، Jose A. S. نويسنده , , Silva، Vera L. M. نويسنده , , Silva، Artur M. S. نويسنده , , Pinto، Diana C. G. A. نويسنده ,

  • Pages
    -1368
  • From page
    1369
  • To page
    0
  • Abstract
    N-Acetyl-styrylpyrazoles undergo Diels-Alder cyclo­addition reactions with N-methylmaleimide under solvent-free conditions to give the corresponding tetrahydroindazoles in good yields and high selectivity. On heating, these reactions do not occur or afford only traces of the cycloadducts. The stereochemistry of ­ obtained cycloadducts was assigned by NMR. Oxidation of the ­tetrahydroindazoles with DDQ gave the expected indazoles and was accompanied by N-deacylation.
  • Keywords
    4-styrylpyrazoles , dehydrogenation , microwave irradiation , indazoles , N-methylmaleimide , Diels-Alder cycloadditions
  • Journal title
    Astroparticle Physics
  • Record number

    111151

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=111151