Title of article :
Synthetic Studies towards (-)-Lemonomycin, Synthesis of Fused Tetracycles
Author/Authors :
Couturier، Cedric نويسنده , , Zhu، Jieping نويسنده , , Schlama، Thierry نويسنده ,
Abstract :
The asymmetric synthesis of 1,3-lactol-bridged tetrahydroisoquinoline 5 is developed. Subsequent cyclization of 5 under acidic conditions leads to the formation of a tricyclic enamide 22, which is in turn converted to a tetracyclic compound 23.
Keywords :
lemonomycin , Amino acid , tetrahydroisoquinoline , Mannich rection , intramolecular Pictet-Spengler reaction
Journal title :
Astroparticle Physics
