Title of article :
Enantioselective Synthesis of (+)-(S,S)-Reboxetine
Author/Authors :
Siddiqui، Shafi A. نويسنده , , Narkhede، Umesh C. نويسنده , , Lahoti، Rajgopal J. نويسنده , , Srinivasan، Kumar V. نويسنده ,
Abstract :
An efficient enantioselective synthesis leading directly to (+)-(S,S)-reboxetine has been described from commercially available trans-cinnammyl bromide using Sharpless asymmetric dihydroxylation as the key step.
Keywords :
dihydroxylation , reboxetine , trans-cinnamyl bromide , hydrogenation , coupling
Journal title :
Astroparticle Physics