Title of article :
Enhancement of the sliding velocity of actin filaments in the presence of ATP analogue: AMP-PNP Original Research Article
Author/Authors :
Junʹichi Sakamaki، نويسنده , , Hajime Honda، نويسنده , , Eiʹichi Imai، نويسنده , , Kuniyuki Hatori، نويسنده , , Katsuhiko Shimada، نويسنده , , Koichiro Matsuno، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2003
Abstract :
The sliding velocity of actin filaments was found to increase in the presence of ATP analogues. At 0.5 mM ATP, the presence of 2.0 mM of AMP-PNP enhanced the filament velocity from 3.2 up to 4.5 μm/s. However, 2 mM ADP decreased the velocity down to 1.1 μm/s. The results suggest that the complex conformations of myosin cross-bridges interacting with an actin filament in the presence of ATP analogues makes the entire filament move faster.
Keywords :
Weakly bound state , actin , myosin , Sliding velocity , ATP analogue
Journal title :
Biophysical Chemistry
Journal title :
Biophysical Chemistry
