Interaction of K7Fe3+P2W17O62H2 with supported bilayer lipid membranes on platinum electrode Original Research Article

The influence of K7Fe3+P2W17O62H2 on l-α-phosphatidylcholine/cholesterol bilayer lipid membrane on Pt electrode was studied by voltammetry and AC impedance spectroscopy. The interaction of the polyoxometalates with the BLM can promote the access of Ru(NH3)63+ and [Fe(CN)6]3−/4− to the electrode surface. It was found that some kind of pores had been formed on the BLM by AFM. The phenomenon is attributed to the interaction of K7Fe3+P2W17O62H2 with phosphatidylcholine phosphate groups located in its outer leaflet. Experimental results are helpful to understand the biological activity of the polyoxometalates in vivo.