A facile synthesis of amides by selective hydration of nitriles using modified natural phosphate and hydroxyapatite as new catalysts Original Research Article

The selective hydration of several nitriles has been accomplished using sodium nitrate modified natural phosphate (NP) and hydroxyapatite (HAP). The corresponding amides were obtained efficiently and selectively in good yields. This reaction was carried out under eco-friendly conditions using water in the absence of organic solvents.