Author/Authors :
Vasiliki Sarli، نويسنده , , Athanassios Giannis، نويسنده ,
Abstract :
In this issue of Chemistry & Biology, Mantelingu and colleagues present the development of the garcinol derivative LTK-14, which is a specific and nontoxic inhibitor of histone acetyltransferase p300-HAT . Interestingly, it blocks histone acetylation of HIV-infected cells resulting in inhibition of the multiplication of HIV in these cells.
