Author/Authors :
Soichiro Yamaguchi، نويسنده , , Shmuel Muallem، نويسنده ,
Abstract :
The intracellular TRPML channels have multiple biological roles, but the physiological stimuli that open them remained unknown. In a previous issue of Chemistry & Biology, Grimm et al. report a high-throughput chemical screen that identified a plethora of selective activators of TRPML3 that should open the way to fully characterize these channels and their physiological roles.
