• Title of article

    CDK9 Inhibitors Push Cancer Cells over the Edge

  • Author/Authors

    Matthew W. Nowicki، نويسنده , , Malcolm D. Walkinshaw، نويسنده ,

  • Issue Information
    ماهنامه با شماره پیاپی سال 2010
  • Pages
    2
  • From page
    1047
  • To page
    1048
  • Abstract
    The trouble with CDK active-site inhibitors is their tendency to have off-target effects. This is not surprising, as the ATP binding sites of most protein kinases are very similar. have used some clever screening approaches to identify selective CDK9 inhibitors that drive cancer cells into apoptosis.
  • Journal title
    Chemistry and Biology
  • Serial Year
    2010
  • Journal title
    Chemistry and Biology
  • Record number

    1159932

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1159932