Prohibitin(g) Cancer: Aurilide and Killing by Opa1-Dependent Cristae Remodeling
Author/Authors :
Martina Semenzato، نويسنده , , Sara Cogliati، نويسنده , , Luca Scorrano، نويسنده ,
Issue Information :
ماهنامه با شماره پیاپی سال 2011
Pages :
2
From page :
8
To page :
9
Abstract :
Proapoptotic drugs targeting the mitochondrial Bcl-2 rheostat of apoptosis are tools to selectively kill cancer cells. expand the available toolkit by identifying the target of the cytotoxic natural product aurilide in the prohibitin Opa1-dependent apoptotic cristae remodeling.