• Title of article

    Bypassing GPCRs with Chemical Dimerizers

  • Author/Authors

    J. Goedhart، نويسنده , , T.W.J. Gadella Jr.، نويسنده ,

  • Issue Information
    ماهنامه با شماره پیاپی سال 2011
  • Pages
    2
  • From page
    1067
  • To page
    1068
  • Abstract
    G protein-coupled receptors (GPCRs) activate heterotrimeric G protein complexes. In this issue, describe a rapamycin-based system to bypass the GPCR by direct activation of a specific heterotrimeric G protein subunit, which induces downstream signaling cascades.
  • Journal title
    Chemistry and Biology
  • Serial Year
    2011
  • Journal title
    Chemistry and Biology
  • Record number

    1160110

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1160110