Author/Authors :
Natsuo Ueda، نويسنده , , Kazuhito Tsuboi، نويسنده ,
Abstract :
Monoacylglycerol lipase (MAGL) deactivates 2-arachidonoylglycerol (2-AG), an endogenous ligand of cannabinoid receptors (endocannabinoid). In this issue of Chemistry & Biology, Chang and colleagues report an extremely specific MAGL inhibitor that should be useful to distinguish between actions of 2-AG and anandamide, another endocannabinoid.
