Author/Authors :
Iole Pitino، نويسنده , , Cinzia Lucia Randazzo، نويسنده , , Giuseppina Mandalari، نويسنده , , Alberto Lo Curto، نويسنده , , Richard Martin Faulks، نويسنده , , Yvan Le Marc، نويسنده , , Carlo Bisignano، نويسنده , , Cinzia Caggia، نويسنده , , Martin Sean John Wickham، نويسنده ,
Abstract :
In the present study six probiotic Lactobacillus rhamnosus strains were investigated for their ability to survive in the human upper gastrointestinal tract through a dynamic gastric model of digestion. MRS broth was used as delivery vehicle and survival was investigated during in vitro gastric and gastric plus duodenal digestion. Results highlighted that all tested strains showed good survival rate during both gastric and duodenal digestion. In particular, three strains exhibited a great survival showing a recovery percentage in the range between 117 and 276%. In agreement with survival data, high lactic acid production was detected for all strains, confirming their metabolic activity during digestion.
Keywords :
Gastrointestinal tract , Lactobacillus rhamnosus , Probiotic , Dynamic gastric model
