Prediction of the progress of solid-state reactions under different temperature modes

Using a computational method (AKTS-TA-Software) for solid-state kinetic analysis, the calculations of the progress of solid-state reactions were achieved employing temperature conditions different from those at which the experiments were carried out. The prediction of the solid-state reaction extent is illustrated by the results obtained during decomposition of hydromagnesite (component of some pharmaceuticals). The applied method was used for the prediction of the reaction progress under different temperature modes such as isothermal, non-isothermal, stepwise, adiabatic, modulated and, additionally for temperature profiles reflecting real atmospheric temperature changes. A comparison between calculated and experimental data is presented.