Author/Authors :
J. Axel Zeitler، نويسنده , , David A. Newnham، نويسنده , , Philip F. Taday، نويسنده , , Clare J. Strachan، نويسنده , , Michael Pepper، نويسنده , , Keith C. Gordon، نويسنده , , Thomas Rades، نويسنده ,
Abstract :
In this study for the first time temperature dependent terahertz pulsed spectroscopy was performed on a pharmaceutical drug. The polymorphic conversion process of carbamazepine form III to I was studied at varying temperatures. Furthermore, the solid-state transformation at isothermal conditions below the melting point of carbamazepine was investigated. The ability to study solid-state reactions with terahertz pulsed spectroscopy could be demonstrated.
