Title of article :
Inclusion complex of fenbufen with (beta)-cyclodextrin
Author/Authors :
Bratu، I. نويسنده , , Gavira-Vallejo، J. M. نويسنده , , Hernanz، A. نويسنده , , Bogdan، M. نويسنده , , Bora، Gh. نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2004
Abstract :
An inclusion complex of fenbufen with (beta)-cyclodextrin ((beta)-CD) in aqueous solution was characterized by 1HNMR spectroscopy. The [1:1] stoichiometry was determined and a stability constant of several 1000s (M^-1) was calculated. The geometry of the inclusion complex was established based on MM+ molecular mechanics calculations.
Keywords :
stoichiometry , Molecular modeling , Stability constant , 1H-NMR , (beta)-Cyclodextrin , antiinflammatory drugs , inclusion complexes , fenbufen
Journal title :
BIOPOLYMERS (ORIGINAL RESEARCH ON BIOMOLECULES)
Journal title :
BIOPOLYMERS (ORIGINAL RESEARCH ON BIOMOLECULES)
