Study of poly(lactic-co-glycolic acid) interactions with collagen

Poly(lactic-co-glycolic acid) (PLGA) is excellent to fabricate drug delivery systems that prolong the release of recombinant human growth hormone (rhGH), with current research focusing on their possible use for bone regeneration in odontological practice. Herein, we evaluate PLGA interactions with a component of the buccal cavity, as collagen, using monolayers and differential scanning calorimetry (DSC) techniques. Our results indicate that interactions in the PLGA–collagen mixtures showed no phase separation and attraction forces were detected irrespective of the concentration ratio.