Synthesis, spectral characterization and antihaemostatic activity of 1,2,4-triazoles incorporating 1,2,4-triazine rings

A simple and high yielding method for the integration of a 1,2,4-triazole ring with 1,2,4-triazine- 5-one (4a–j) has been developed starting from 3-arylsydnones (1a–d). The structures were proved by their spectral data and screened for antihaemostatic activity.