Author/Authors :
Alavandi، Shwetha نويسنده Toxicology Laboratory, Department of Studies and Research in Applied Zoology, Kuvempu University, Jnana Sahyadri, Shankaraghatta – 577451, Karnataka, India , , Hosetti، Basaling B. نويسنده Toxicology Laboratory, Department of Studies and Research in Applied Zoology, Kuvempu University, Jnana Sahyadri, Shankaraghatta – 577451, Karnataka, India ,
Abstract :
Sublethal toxicity of cyanide to freshwater fish, Cirrhinus mrigala
was evaluated to determine its effect on the activities of some antioxidative
enzymes. Changes in succinate dehydrogenase (SDH), lactate dehydrogenase
(LDH) and glucose-6-phosphate dehydrogenase (G6-PDH) were observed in
tissues of the tested animal. Cyanide significantly decreased the activity of SDH,
and G6-PDH in the liver, gill and brain tissues of the fish. The elevation of LDH
indicated metabolic disorders and a clear response against energy depletion.
Changes in the dehydrogenase activity in cyanide treated fish tissues may be due to
fluctuations in oxidative metabolism. It is concluded that the cyanide intoxication
exerted a profound impact on the enzymatic activity of the fish, as observed in the
hitherto study.
