Title of article
Polypeptide grafted hyaluronan: A self-assembling comb-branched polymer constructed from biological components
Author/Authors
Madhuvanthi A. Kandadai، نويسنده , , Rajasekhar Anumolu، نويسنده , , Xiaojun Wang، نويسنده , , Durairaj Baskaran، نويسنده , , Leonard F. Pease III، نويسنده , , Dmitry Bedrov، نويسنده , , Grant D. Smith، نويسنده , , Jimmy W. Mays، نويسنده , , Jules J. Magda، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2011
Pages
6
From page
2022
To page
2027
Abstract
Rheological evidence is provided demonstrating that covalent grafting of monodisperse isotactic poly(l-leucine) branches onto linear hyaluronan (HA) polysaccharide chains yields comb-branched HA chains that self-assemble into long-lived physical networks in aqueous solutions driven by hydrophobic interactions between poly(l-leucine) chains. This is in stark contrast to native (unmodified) HA solutions which exhibit no tendency to form long-lived physical networks.
Keywords
Viscoelasticity , Hyaluronic acid , Polypeptide , Hydrophobic interaction
Journal title
European Polymer Journal(EPJ)
Serial Year
2011
Journal title
European Polymer Journal(EPJ)
Record number
1228902
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