Author/Authors :
Gorka Orive Arroyo، نويسنده , , Rosa M. Hern?nedez، نويسنده , , Alicia R. Gasc?n، نويسنده , , Manoli Igartua، نويسنده , , José Luis Pedraz، نويسنده ,
Abstract :
Diabetes affects 150 million people worldwide and results from abnormal function of pancreatic islets. The scarcity of human tissue donors has focused interest in developing renewable sources of insulin-producing cells appropriate for engraftment. Advances in stem cell technology and transdifferentiation techniques have provided powerful tools to study pancreatic development, function and disease. Recent results from these two approaches could have significant implications for future therapies of diabetes.