Using electropolymerized non-conducting polymers to develop enzyme amperometric biosensors

The response performance of amperometric biosensors can be likened to that of an uncovered electrode because the non-conducting polymer films used to develop these biosensors are very thin (10–100 nm), owing to their self-limited growth. The non-conducting polymer films also have favorable permselective properties, which could be used to eliminate possible electrochemical interference in samples. Composite structures or materials that include non-conducting polymers of, for example, phenol and its derivatives, phenylenediamines, and overoxidized or electroinactive polypyrrole could be used to optimize the biosensors. This article will discuss these issues, as well as the use of quartz crystal microbalance in the study of non-conducting-polymer-based biosensors.