Author/Authors :
Nicholas M. Luscombe، نويسنده , , M. Madan Babu، نويسنده ,
Abstract :
Microarrays have become indispensable tools for studying the gene expression of particular organisms on a genomic scale. However, despite its widespread use, there are several draw-backs to the current technology. First, it requires prior knowledge of the DNA sequence encoded in the organism of interest, and second, chips must be designed specifically for each genome, greatly increasing the initial cost incurred in manufacturing the arrays.