Title of article
Basic chiral ionic liquids: A novel strategy for acid-free organocatalysis
Author/Authors
Maria Vasiloiu، نويسنده , , Daniel Rainer، نويسنده , , Peter Gaertner، نويسنده , , Christian Reichel، نويسنده , , Christian Schr?der، نويسنده , , Katharina Bica، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2013
Pages
7
From page
80
To page
86
Abstract
We present design, synthesis and application of basic chiral ionic liquids based on commercially available (S)-proline. This new set of chiral ionic liquids was specifically designed to replace trifluoroacetic acid in enamine-based organocatalysis for asymmetric Csingle bondC bond formation. Based on their permanent charge, these chiral ionic liquids could be applied as organocatalysts in asymmetric aldol reaction of 4-nitrobenzaldehyde and acetone, and good yields and selectivities up to 80%ee could be obtained without additional acid.
Keywords
Ionic liquids , aldol reaction , asymmetric synthesis , Chirality , organocatalysis
Journal title
CATALYSIS TODAY
Serial Year
2013
Journal title
CATALYSIS TODAY
Record number
1239006
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