Title of article :
Fast and Slow Intermediate Accumulation and the Initial Barrier Mechanism in Protein Folding
Author/Authors :
Bryan A. Krantz، نويسنده , , Leland Mayne، نويسنده , , Jon Rumbley، نويسنده , , S.Walter Englander، نويسنده , , Tobin R. Sosnick، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2002
Abstract :
Do stable intermediates form very early in the protein folding process? New results and a quantity of literature that bear on this issue are examined here. Results available provide little support for early intermediate accumulation before an initial search-dependent nucleation barrier.
Keywords :
Protein folding , burst phase , barriers in protein folding , intermediates in protein folding , initial barrier hypothesis
Journal title :
Journal of Molecular Biology
Journal title :
Journal of Molecular Biology