Title of article :
Enteroaggregative Escherichia coli, a heterogenous, underestimated and under-diagnosed E. coli pathotype in Iran
Author/Authors :
Jafari، Anis نويسنده , , Aslani، Mohammad-Mehdi نويسنده Department of Microbiology, Pasteur Institute of Iran, Tehran, Iran , , Bouzari، Saeid نويسنده ,
Issue Information :
فصلنامه با شماره پیاپی سال 2013
Abstract :
The main features of enteroaggregative Escherichia coli (EAEC) pathogenesis include attachment of bacteria to the
intestinal mucosa, production of various toxins and cytotoxins, and stimulation of mucosal inflammation. ‘Virulence’
genes encode these features. Comparison of different EAEC isolates has shown that the virulence gene content of these
isolates varies considerably. The heterogeneity of EAEC strains was concluded from the results obtained from the
volunteer as well as other studies. Although the underlying mechanism behind the apparent increase in O104:H4
virulence is not known, several bacterial factors have been implicated. In this review, the known virulence factors
involved in pathogenesis of EAEC pathotype are summarized.
Journal title :
Gastroenterology and Hepatology From Bed to Bench
Journal title :
Gastroenterology and Hepatology From Bed to Bench