• Title of article

    Single-cell Analysis of λ Immunity Regulation

  • Author/Authors

    Kristoffer B?k، نويسنده , , Sine Svenningsen، نويسنده , , Harvey Eisen، نويسنده , , Kim Sneppen، نويسنده , , R.Stanley Brown، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2003
  • Pages
    10
  • From page
    363
  • To page
    372
  • Abstract
    We have examined expression of the λcI operon in single cells via a rex∷gfp substitution. Although average fluorescence agreed with expectations for expression of λ-repressor, fluorescence fluctuated greatly from cell-to-cell. Fluctuations in repressor concentration are not predicted by previous models and are tolerated in part by a regulatory response to DNA damage.
  • Keywords
    repressor , single-cell analyses , Bacteriophage lambda , GFP
  • Journal title
    Journal of Molecular Biology
  • Serial Year
    2003
  • Journal title
    Journal of Molecular Biology
  • Record number

    1243183