IFITMs Restrict the Replication of Multiple Pathogenic Viruses Review Article

The interferon-inducible transmembrane protein (IFITM) family inhibits a growing number of pathogenic viruses, among them influenza A virus, dengue virus, hepatitis C virus, and Ebola virus. This review covers recent developments in our understanding of the IFITMʹs molecular determinants, potential mechanisms of action, and impact on pathogenesis.