Mechanism of taste; electrochemistry, receptors and signal transduction

This report describes a novel mechanistic approach based on electrochemistry, receptors and signal transduction. Part A presents limited correlation between dipole moments and associated electrostatic fields (EFs), and taste. For Part B, binding of the tastant to the receptor results in interaction of the ligand EF with those of the protein receptor. Part C addresses passage of the message by the altered EF to the gustatory neurons, involving electrical effects and signal transduction. Insight is gained from external electrical stimulus. Part D represents the final step in which the electrical signal is converted to perceived taste in the brain.