In vitro hydroxiapatite formation on the Ca doped surface of ZSM-5[Ga] type zeolite

A high SiO2/Al2O3 ratio ZSM-5[Ga] type zeolite was synthesized. Then an ionic exchange of Na by Ca ions on the surface was performed. The in vitro bioactivity was assessed by immersing samples in Simulated Body Fluid (SBF) for different periods of time. Bonelike apatite was formed on the zeolite as early as 7 days of immersion. This indicates that this ZSM-5[Ga] zeolite with a Ca-functionalized surface is a potential material for bone tissue regeneration.