Abstract :
Gene therapy has been recently shown as a promising tool for cancer treatment as
nanotechnology-based safe and effective delivery methods are developed. Generally, genes
are wrapped up in extremely tiny nanoparticles which could be taken up easily by cancer
cells, not to their healthy neighboring cells. Several nanoparticle systems have been
investigated primarily to address the problems involved in other methods of gene delivery
and observed improved anticancer efficacy suggesting that nanomedicine provides novel
opportunities to safely deliver genes, thus treat cancer. In this review, various nanoparticle
types and related strategies, used in gene delivery for cancer treatment, have been
discussed.