Author/Authors :
J. M. Crance، نويسنده , , V. Apaire-Marchais، نويسنده , , F. Lévêque، نويسنده , , C. Beril، نويسنده , , F. Le Guyader، نويسنده , , A. Jouan، نويسنده , , L. Schwartzbrod، نويسنده , , S. Billaudel، نويسنده ,
Abstract :
Twenty-two mussel and cockle samples were collected after a hepatitis A outbreak on the Atlantic coast, in France. Detection of hepatitis A virus (HAV) antigen by radioimmunoassay and HAV RNA by hybridization were negative. However, HAV RNA was detected by reverse transcription and semi-nested polymerase chain reaction in 16 samples, and replication in cell culture was observed with four of them.
