Title of article :
Beer increases plasma antioxidant capacity in humans
Author/Authors :
Andrea Ghiselli، نويسنده , , Fausta Natella، نويسنده , , Alessia Guidi، نويسنده , , Luigi Montanari، نويسنده , , Paolo Fantozzi، نويسنده , , Cristina Scaccini، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2000
Pages :
5
From page :
76
To page :
80
Abstract :
The positive association of a moderate intake of alcoholic beverages with a low risk for cardiovascular disease, in addition to ethanol itself, may be linked to their polyphenol content. This article describes the effect of acute ingestion of beer, dealcoholized beer, and ethanol (4.5% v/v) on the total plasma antioxidant status of subjects, and the change in the high performance liquid chromatography profile of some selected phenolic acids (caffeic, sinapic, syringic, and vanillic acids) in 14 healthy humans. Plasma was collected at various times: before (T0), 1 hour after (T1), and 2 hours after (T2) drinking. The study is part of a larger research planned to identify both the impact of brewing on minor components potentially present in beer and their metabolic fate in humans. Beer was able to induce a significant (P < 0.05) increase in plasma antioxidant capacity at T1 (mean ± SD: T0 1,353 ± 320 μM; T1 1,578 ± 282 μM), returning close to basal values at T2. All phenolic acids measured in plasma tended to increase after beer intake (20% at T1, 40% at T2). Syringic and sinapic acid reached statistical significance (P < 0.05 by one-way analysis of variance-Fisher’s test) at T1 and T2, respectively. Plasma metabolic parameters (glucose, total cholesterol, triglycerides, and uric acid) and plasma antioxidants (α-tocopherol and glutathione) remained unchanged. Ethanol removal impaired the absorption of phenolic acids, which did not change over the time of the experiment, accounting for the low (and not statistically significant) increase in plasma antioxidant capacity after dealcoholized beer drinking. Ethanol alone did not affect plasma antioxidant capacity or any of the antioxidant and metabolic parameters measured.
Keywords :
Polyphenols , Antioxidants , Beer , Ethanol , TRAP , Human
Journal title :
The Journal of Nutritional Biochemistry
Serial Year :
2000
Journal title :
The Journal of Nutritional Biochemistry
Record number :
1296630
Link To Document :
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