Title of article
TNFα gene knockout differentially affects lipid deposition in liver and skeletal muscle of high-fat-diet mice
Author/Authors
Jérôme Salles، نويسنده , , Nicolas Tardif، نويسنده , , Jean-François Landrier، نويسنده , , Isabelle Mothe-Satney، نويسنده , , Christelle Guillet، نويسنده , , Carole Boue-Vaysse، نويسنده , , Lydie Combaret، نويسنده , , Christophe Giraudet، نويسنده , , Véronique Patrac، نويسنده , , Justine Bertrand-Michel، نويسنده , , Philippe Denis، نويسنده , , Jean-Michel Chardigny، نويسنده , , Yves Boirie، نويسنده , , Stéphane Walrand، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2012
Pages
9
From page
1685
To page
1693
Abstract
Inflammation and ectopic lipid deposition contribute to obesity-related insulin resistance (IR). Studies have shown that deficiency of the proinflammatory cytokine tumor necrosis factor-α (TNFα) protects against the IR induced by a high-fat diet (HFD). We aimed to evaluate the relationship between HFD-related inflammation and lipid deposition in skeletal muscle and liver.
Keywords
Fibrosis , Lipotoxicity , TNF?-KO mice , High-fat diet , Inflammation
Journal title
The Journal of Nutritional Biochemistry
Serial Year
2012
Journal title
The Journal of Nutritional Biochemistry
Record number
1300092
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