Title of article :
Anti-AIDS agents. Part 36: 17-carboxylated steroids as potential anti-HIV agents Original Research Article
Author/Authors :
Peng-Xia Liu، نويسنده , , Zhengyu Yang، نويسنده , , Yi Xia، نويسنده , , Yun-Qing Zheng، نويسنده , , L. Mark Cosentino، نويسنده , , Kuo-Hsiung Lee، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1999
Abstract :
In our search for novel anti-HIV agents, seven 17-carboxylated steroid derivatives were synthesized and evaluated as potential anti-HIV agents. Compound exhibited potent anti-HIV activity in acutely infected H9 lymphocytes with EC50 and therapeutic index values of 0.8 μM and 300, respectively.
Keywords :
Anti-HIV , 17-carboxylated steroid
Journal title :
Bioorganic and Medicinal Chemistry
Journal title :
Bioorganic and Medicinal Chemistry
