Title of article
Synthesis and biological evaluation of 2-methoxy- and 2-Methylthio-6-[(2′-alkylamino)ethyl]-4(3H)-pyrimidinones with anti-rubella virus activity Original Research Article
Author/Authors
Maurizio Botta، نويسنده , , Francesca Occhionero، نويسنده , , Rosario Nicoletti، نويسنده , , Paola Mastromarino، نويسنده , , Cinzia Conti، نويسنده , , Maurizio Magrini، نويسنده , , Raffaele Saladino، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
7
From page
1925
To page
1931
Abstract
The synthesis of a new family of antiviral compounds, 2-methoxy-, and 2-methylthio-6-[(2′-alkylamino)ethyl]-4(3H)-pyrimidinones, has been accomplished. The activity of these agents against positive strand (rubella virus and sindbis virus) and negative strand (vesicular stomatitis virus) RNA viruses is reported. Some of these compounds are efficient and selective inhibitors of rubella virus.
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
1999
Journal title
Bioorganic and Medicinal Chemistry
Record number
1300480
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