Author/Authors :
Marina Gordaliza، نويسنده , , JoséM. Miguel del Corral، نويسنده , , M. Angeles Castro، نويسنده , , M. Luisa L?pez-V?zquez، نويسنده , , Arturo San Feliciano، نويسنده , , M. Dolores Garc?a-Gr?valos، نويسنده , , Alain Carpy، نويسنده ,
Abstract :
A series of fused pyrazole derivatives of cyclolignans have been prepared through simple chemical routes and evaluated for their cytotoxic activities in culture cells of P-388 murine leukemia, A-549 lung carcinoma and HT-29 colon carcinoma. Despite the lack of the lactone moiety in their structures, they show IC50 values at μM levels.
