Title of article
Synthesis and antitumor activity of goniofufurone analogues Original Research Article
Author/Authors
Hari Babu Mereyala، نويسنده , , Rajendrakumar Reddy Gadikota، نويسنده , , Maju Joe، نويسنده , , Sudershan K. Arora، نويسنده , , Sunanda G. Dastidar، نويسنده , , Sudhanshu Agarwal، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
9
From page
2095
To page
2103
Abstract
Synthesis and antitumor activity of goniofufurone analogues , , , , and is reported. Key step in the synthesis is Pd (II) mediated oxidative cyclisation of vinyl-(hydroxy) furans , to the corresponding lactols , . Cytotoxicities of , , , , and tested against six human cancer cell lines are reported. Change of stereochemistry at C-5, C-6 and C-7 position of goniofufurone () did not enhance the cytotoxicities significantly.
Keywords
Goniofufurone , Antitumour , palladium (II) chloride , Diastereomers
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
1999
Journal title
Bioorganic and Medicinal Chemistry
Record number
1300539
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