Title of article
design and synthesis of a novel series of HIV-1 protease inhibitors Original Research Article
Author/Authors
Eiji Takashiro، نويسنده , , Yuji Nakamura، نويسنده , , Shuichi Miyamoto، نويسنده , , Yuji Ozawa، نويسنده , , Akiko Sugiyama، نويسنده , , Katsumi Fujimoto، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
10
From page
2105
To page
2114
Abstract
The synthesis and the SAR study of novel pseudo symmetric inhibitors of HIV-1 protease are described. Michael addition of amino acid derivatives to vinyl ketones was utilized to derive a potent (nM) series of HIV-1 protease inhibitors.
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
1999
Journal title
Bioorganic and Medicinal Chemistry
Record number
1300540
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