Title of article
Synthesis of 2-isoxazoline and α-hydroxy ketomethylene dipeptide isosteres Original Research Article
Author/Authors
Yong Jun Chung، نويسنده , , Eun Jung Ryu، نويسنده , , Gyochang Keum، نويسنده , , Kim Byeang Hyean، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
17
From page
209
To page
225
Abstract
We have developed a simple and stereoselective method for synthesizing novel dipeptide isosteres using nitrite oxide cycloaddition as a key reaction. Employing this method, we have prepared efficiently various peptidomimetics containing 2-isoxazolines and α-hydroxy ketomethylene dipeptide isosteres.
Keywords
nitrile oxide cycloaddition , peptidomimetics , ?-hydroxy ketomethylene , 2-isoxazoline , Dipeptide isostere
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
1996
Journal title
Bioorganic and Medicinal Chemistry
Record number
1300632
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