Title of article
Synthesis and BZR affinity of pyrazolo[1,5-a]pyrimidine derivatives. part 1: study of the structural features for BZR recognition Original Research Article
Author/Authors
Silvia Selleri، نويسنده , , Fabrizio Bruni، نويسنده , , Camilla Costagli، نويسنده , , Annarella Costanzo، نويسنده , , Gabriella Guerrini، نويسنده , , Giovanna Ciciani، نويسنده , , Barbara Costa، نويسنده , , Claudia Martini، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
7
From page
2705
To page
2711
Abstract
Examination of the pharmacophoric points of the pyrazolo[1,5-a]pyrimidine derivatives, ligands for BZR, previously published led us to the design of a novel class of 3,6-diaryl-4,7-dihydro-pyrazolo[1,5-a]pyrimidin-7-ones and to determine the groups involved in the BZR recognition.
Keywords
partial agonists. , structure–affinity relationship (SAFIR) , Benzodiazepine receptor (BZR) binding studies , 5-a]pyrimidine derivatives
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
1999
Journal title
Bioorganic and Medicinal Chemistry
Record number
1300681
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