Title of article
Inhibition of adhesion molecule expression by N-alkylthiopyridine-benzo[b]thiophene-2-carboxamides Original Research Article
Author/Authors
Diane H. Boschelli، نويسنده , , David T. Connor، نويسنده , , Mark E. Lesch، نويسنده , , Denis J. Schrier، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
6
From page
557
To page
562
Abstract
The surface levels of ICAM-1 and E-selectin on activated endothelial cells can be reduced by 3-alkoxybenzo[b]thiophene-2-carboxamides. This property is shared by several N-alkylthiopyridine substituted imides. Combining structural elements of these two diverse series lead to a new class of small molecule inhibitors of adhesion molecule expression.
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
1996
Journal title
Bioorganic and Medicinal Chemistry
Record number
1300733
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